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. Author manuscript; available in PMC: 2021 Mar 23.
Published in final edited form as: J Immunol Methods. 2013 Nov 23;402(1-2):57–70. doi: 10.1016/j.jim.2013.11.011

Figure 7. Measurement and ROC Analysis of Serum GMAb Concentration in Autoimmune PAP Patients and Healthy Controls.

Figure 7.

A. Serum GMAb levels in Autoimmune PAP Patients and Healthy People. Serum GMAb concentration was measured using the GMAb ELISA with the PCRS in 44 autoimmune PAP patients and 38 healthy controls as described in the text.

B. Histogram of the Distribution of Serum GMAb Concentrations in Autoimmune PAP Patients and Healthy People. Data represented as a frequency distribution of serum GMAb concentrations in autoimmune PAP patients (filled bars) and healthy people (hatched bars).

C.-D. Receiver Operating Characteristic (ROC) Curve Analysis of Serum GMAb ELISA Test Results for 44 Autoimmune PAP Patients and 38 Healthy People. Standard ROC characteristic analysis was performed to determine the sensitivity and specificity for the data shown in Panel A. The area under the curve was 1.0 (C), and, at a cut off value for GMAb of 5.0 μg/ml determined by the software, the sensitivity and specificity of the GMAb ELISA were both 100% (D).