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. 2021 Mar 16;23(5):368. doi: 10.3892/mmr.2021.12007

Figure 2.

Figure 2.

miR-122-5p is downregulated in PTC specimens. (A) miR-122-5p expression in 45 pairs of PTC tissues and adjacent non-cancerous tissues. ***P<0.001 by Wilcoxon signed-rank test. (B) miR-122-5p expression in 21 PTC specimens with metastasis and 24 non-metastatic PTC specimens. ***P<0.001 by Wilcoxon rank sum test. (C) miR-122-5p expression in 27 PTC specimens with diameters >3 cm and 18 PTC specimens with diameters <3 cm. Results are presented as the median with interquartile range. **P<0.01 by Wilcoxon rank sum test. (D) miR-122-5p expression in normal thyroid epithelial cell line FRTL-5, thyroid cancer cell line BCPAP and PTC cell lines TPC-1, K1. Results are presented as the mean ± SEM from three independent experiments. ***P<0.001 by one-way ANOVA. miR, microRNA; PTC, papillary thyroid carcinoma.