Skip to main content
. Author manuscript; available in PMC: 2021 Mar 23.
Published in final edited form as: Cell Rep. 2021 Mar 2;34(9):108797. doi: 10.1016/j.celrep.2021.108797

Figure 2. Type II topoisomerase inhibition results in increased DnaC accumulation at HO genes.

Figure 2.

DnaC ChIP-seq profiles of cells carrying either an HO (blue, strain HM3863) or CD (red, strain HM2864) lacZ engineered conflict, with and without novobiocin treatment (375 ng/mL). Normalized signal is the read depth of IP/input normalized to the total number of reads. The direction of DNA replication is left to right. Direction of transcription is indicated by the promoter arrow on lacZ.

See also Figure S2 and Table S3.