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. 2020 Dec 16;16(5):767–776. doi: 10.1002/cmdc.202000771

Figure 3.

Figure 3

Chemical structure of tacrolimus (2) and some representative, unnatural precursors that were successfully incorporated by mutasynthesis and/or combinatorial biosynthesis.[ 50 , 51 , 52 , 53 , 54 , 55 , 56 ]