Table 2.
Clinical characteristics of adults with RSV-associated hospitalization, 2015–2017
| Clinical characteristics (number of patients), n (%) | |||||
|---|---|---|---|---|---|
| Percent of individuals living below the poverty level within a census tract | Total (n = 1713) | ||||
| Underlying conditions |
0–4.9% (n = 397) |
5–9.9% (n = 535) |
10–19.9% (n = 438) |
≥20% (n = 343) |
|
| Any underlying medical condition | 377 (95) | 508 (95) | 409 (93) | 321 (94) | 1615 (94) |
| Pulmonary disease1 | 166 (42) | 279 (52) | 211 (39) | 215 (63) | 871 (51) |
| Obesity (BMI ≥30) | 203 (51) | 244 (46) | 212 (48) | 158 (46) | 817 (48) |
| Chronic metabolic disease2 | 171 (43) | 269 (32) | 189 (35) | 163 (48) | 792 (46) |
| Cardiovascular disease3 | 170 (43) | 245 (46) | 182 (42) | 156 (45) | 753 (44) |
| Renal disease4 | 95 (24) | 163 (30) | 126 (29) | 106 (31) | 490 (29) |
| Immunocompromised5 | 104 (26) | 136 (25) | 89 (17) | 93 (27) | 422 (25) |
| Neurologic disease6 | 87 (22) | 105 (20) | 91 (17) | 64 (19) | 347 (20) |
| Liver disease7 | 20 (5) | 29 (7) | 22 (5) | 30 (9) | 101 (6) |
| Blood disorders/hemoglobinopathy8 | 16 (4) | 17 (3) | 16 (3) | 10 (3) | 59 (3) |
| Rheumatologic disease 9 | 18 (5) | 17 (3) | 15 (3) | 22 (6) | 72 (4) |
| Substance Use | |||||
| Smoker (current) | 39 (10) | 64 (12) | 88 (20) | 101 (29) | 292 (17) |
| Smoker (former) | 153 (39) | 178 (33) | 131 (30) | 105 (31) | 567 (33) |
| Smoker (no/unknown) | 205 (52) | 293 (55) | 219 (50) | 137 (40) | 854 (50) |
| Alcohol abuse (current) | 8 (2) | 11 (2) | 14 (3) | 25 (7) | 58 (3) |
| Alcohol abuse (former) | 13 (3) | 16 (3) | 10 (2) | 13 (4) | 52 (3) |
| Alcohol abuse (no/unknown) | 376 (95) | 508 (95) | 414 (95) | 305 (89) | 1603 (94) |
| Substance abuse (current) | 5 (1) | 8 (1) | 10 (2) | 28 (8) | 51 (3) |
| Substance abuse (former) | 2 (1) | 3 (1) | 2 (0) | 9 (3) | 16 (1) |
| Substance abuse (no/unknown) | 390 (98) | 524 (98) | 426 (98) | 306 (89) | 1646 (96) |
| Indicators of Severe Illness | |||||
| Hospital stay > 7 days | 103 (26) | 110 (21) | 106 (24) | 103 (30) | 422 (25) |
| ICU admission | 86 (22) | 92 (17) | 86 (20) | 80 (23) | 344 (20) |
| Need for mechanical ventilation | 32 (8) | 39 (7) | 35 (8) | 37 (11) | 143 (8) |
| Death | 19 (5) | 28 (5) | 21 (5) | 18 (5) | 86 (5) |
1asthma, COPD, chronic bronchitis, emphysema, CF, Chronic respiratory failure, active TB, other
2diabetes, thyroid disease, other endocrinopathy
3coronary artery disease, congestive heart failure, cardiomyopathy, prior coronary artery bypass graft, cerebral vascular accident/stroke/transient ischemic attack, atherosclerosis
4chronic kidney disease, end-stage renal disease, glomerulonephritis, nephrotic syndrome, other
5cancer, complement deficiency, HIV, AIDS, immunoglobulin deficiency, any immunosuppressive therapy, status-post solid organ transplant, s/p bone marrow transplant, receipt of steroid therapy, other
6cerebral palsy, cognitive dysfunction, dementia, developmental delay, Trisomy 21, paralysis, seizures, muscular dystrophy, multiple sclerosis, myasthenia gravis, other
7cirrhosis, hepatitis B or C, other
8aplastic anemia, Sickle cell disease, asplenia, other
9lupus, Juvenile idiopathic arthritis, rheumatoid arthritis, psoriasis, polymyositis, polymyalgia, polyarteritis nodosa, vasculitis, other