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Aetiology of ATIN in the cohorts of ICI ATIN and non-ICI-related patients
| ICI related ATIN (n = 13) |
Non-ICI related ATIN (n = 34) |
||
|---|---|---|---|
| Drug | % cases | Drug | % cases |
| Anti-PD-1 | 61.5 | NSAIDs | 29.4 |
| Anti-PD-L1 | 23.1 | Fluoroquinolones | 20.6 |
| Anti-PD-1 + anti-CTLA4 | 7.7 | β-Lactams | 8.8 |
| Anti-PD-L1 + anti-CTLA4 | 7.7 | PPIs | 2.9 |
| Others | 38.2 | ||
The non-ICI-related ATIN cases were attributed to: sitagliptin, rifampicin, repaglinide, fosfomycin, lenalidomide, cocaine, vandetanib and cobimetinib.
