Table 4.

Cases of patients with ATIN relapse, treatment and evolution

Sex/age (years)/ATIN cause	Time to relapse since diagnosis (months)	Prednisone cumulative dose at the moment of relapse (mg)	Relapse cause	Serum creatinine at relapse (mg/dL)	Relapse treatment	Evolution
M/71/anti-PD-1	8	4075	Offending drug re-initiation	2.07	Prednisone 30 mg/day	Normalization of serum creatinine
M/81/anti-PD-1	4	2425	Ciprofloxacin initiation plus decrease in prednisone dose	3.02	Prednisone 30 mg/day	Normalization of serum creatinine
F/83/anti-PD-1	3	2572.5	Prednisone withdrawal	10.59	Methylprednisolone 750 mg (bolus) + prednisone 40 mg/day	Stabilization—creatinine 1.4 mg/dL
M/77/NSAIDs	15	3750	Prednisone withdrawal	2.51	Prednisone 40 mg/day	Stabilization—creatinine 1.5 mg/dL
M/74/amoxicillin	5	4125	Unknown	2.49	Prednisone 30 mg/day	Stabilization—creatinine 2.5 mg/dL
M/66/ciprofloxacin	5	2060	Unknown	2.03	Prednisone 15 mg/day	Stabilization—creatinine 1.5 mg/dL