Skip to main content
. 2021 Feb 21;61(2):263–275. doi: 10.1111/head.14067

TABLE 2.

General publication characteristics (n = 705 total publications)

Study characteristic Percent N
Study purpose(s)
Efficacy assessed 96.6 681
Pharmacokinetic study 4.4 31
Study/design features
Study 1988 or later 94.0 663
Randomized 77.6 547
Blinded 73.3 517
Randomized and blinded 70.1 494
ICHD migraine criteria used 79.4 560
Placebo/Sham controlled 60.6 427
Crossover design 23.0 162
Intervention information
Drug/medical device 96.3 679
Multiple active treatments 36.7 259
Open‐label study 21.8 154
Multiple dose levels assessed 23.8 168