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. 2021 Mar 9;8:635771. doi: 10.3389/fmed.2021.635771

Table 1.

Demographic and clinicopathologic variables of the whole cohort grouped by lymph node status.

Charteristics Total (N = 1,271) No (%) CLNM- (N = 619) CLNM+(N = 652) P-value
Gender <0.001
Male 339 (26.67) 132 (38.94) 207 (61.06)
Female 932 (73.33) 487 (52.25) 445 (47.75)
Age (years) 41.38 ± 11.09 43.18 ± 11.39 39.68 ± 10.51 <0.001
≤55 1,140 (89.69) 534 (46.84) 606 (53.16) <0.001
>55 131 (10.31) 85 (64.89) 46 (35.11)
Tumor size (mm) 9.92 ± 5.69 8.53 ± 4.27 11.24 ± 6.34 <0.001
≤10 mm 897 (70.57) 491(54.74) 406 (45.26) <0.001
10–20 mm 305 (24.00) 115 (37.70) 190 (62.30)
>20 mm 69 (5.43) 13 (18.84) 56 (81.16)
Bilateral <0.001
No 1,071 (84.3) 544 (50.79) 527 (49.21)
Yes 200 (15.7) 75 (37.50) 125 (62.50)
Tumor location 0.127
Upper 304 (23.92) 152 (50.00) 152 (50.00)
Middle 545 (42.88) 280 (51.38) 265 (48.62)
Inferior 380 (29.90) 171 (45.00) 209 (55.00)
Isthmus 42 (3.30) 16 (38.10) 26 (61.90)
Multifocality <0.001
Absence 1,002 (78.77) 514 (51.30) 488 (48.70)
Presence 269 (21.23) 105 (39.03) 164 (60.97)
CLT 0.573
No 988 (77.73) 477 (48.28) 511 (51.72)
Yes 283 (22.27) 142 (50.18) 141 (49.82)
DLN status <0.001
Negative 1,051 (82.69) 589 (56.04) 462 (43.96)
Positive 220 (17.31) 30 (13.64) 190 (86.36)

Continuous data are shown as mean ± standard deviation.

–, negative; +, positive; CLNM, central lymph node metastasis; CLT, chronic lymphocytic thyroiditis; DLN, Delphian lymph node.