Skip to main content
. 2020 Apr 15;14(3):876–883. doi: 10.1093/ckj/sfaa026

Table 3.

Renal biopsy findings in patients with MN and viral infection

Deposits
Case no. Virology PLA2R staining THSD7A staining HbS Ag staining Total glomeruli Globally sclerotic glomeruli IFTA (%) IF, IP IgG4 EM stage Sub epithelial Intra membranous Sub endothelial Mesangial TRIs
1 HBV Neg NA Neg 8 0 0 IgG++, IgM+++ NA I–II Yes No No No No
2 HBV Pos NA Neg 16 0 10 Not done Pos++ I–II Yes Yes No No No
3 HBV Pos NA Neg 17 7 30 IgG+, C3+,mesangial IgM+ Pos+++ I–IV Yes Yes No Yes No
4 HBV Pos NA Neg 15 2 10 IgG+ IgM+/−, C3 trace, IgA and C1q: negative Pos+++ II Yes No Yes Yes Yes
5 HBV Neg Pos Neg 21 1 0 IgG++ IgA+/− IgM+/− C3+/− C1q negative Neg I Yes No Yes Yes Yes
6 HBV Pos NA Neg 25 0 0 IgG++ IgM+/− C3+/− IgA and C1q: negative Pos+++ II Yes Yes No Yes Yes
7 HCV Pos NA NA 18 1 15 IgG++, mesangial IgM+, C1q++, C3+ Pos+ II Yes Yes No No Yes
8 HCV Pos NA NA 16 2 5 IgG++, IgM+/−,C3+ Pos++ I–II Yes Yes No Yes No
9 HCV Pos NA NA 16 1 10 IgG+++, C3++ Pos++ II Yes No No No Yes
10 HCV Neg Neg NA 28 0 0 IgG+ Pos+ II Yes Yes No Yes No
11 HIV Neg NA NA 27 5 10 IgG+, IgA+, IgM++, C3++ NA I–IV Yes Yes Yes Yes No
12 HIV Neg Pos NA 23 2 5 IgG+, IgM++, IgA Neg NA I–II Yes Yes No No No
13 HIV Neg Neg NA 35 2 15 IgG+, IgA+,IgM++ C1q+, C3++ Neg I–IV Yes Yes No Yes No
14 HIV Pos NA NA 15 1 0 IgG+, C3+ Neg I–IV Yes Yes No No No
15 HIV Neg Pos NA 15 5 60 IgG++, IgM++, C1q++, C3++ Neg II Yes Yes No Yes No
16 HIV Pos NA NA 12 1 10 IgA+ (segmental), IgG+++, IgM++, Mesangial IgA+, IgM+ Pos ++ III–IV Yes Yes No Yes No
17 HIV HBV Neg Neg Neg 19 4 5 IgG+, IgA++, C3+, C1q++, IgM+ mesangial IgM+ and C1q++ Neg II Yes No Yes No No
18 HIV HBV Pos NA Neg 5 2 5 IgG++, IgM+, segmental IgA+, C3+, C1q+ NA II Yes Yes No Yes No
19 HIV HCV Neg Neg NA 24 3 5 IgG+, scanty mesangial IgA+/−, IgM+/− C3+/− Pos + II Yes No No No No

IFTA: interstitial fibrosis and tubular atrophy; TRIs: tubuloreticular inclusions; NA: not available.