Table 3.
Deposits |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case no. | Virology | PLA2R staining | THSD7A staining | HbS Ag staining | Total glomeruli | Globally sclerotic glomeruli | IFTA (%) | IF, IP | IgG4 | EM stage | Sub epithelial | Intra membranous | Sub endothelial | Mesangial | TRIs |
1 | HBV | Neg | NA | Neg | 8 | 0 | 0 | IgG++, IgM+++ | NA | I–II | Yes | No | No | No | No |
2 | HBV | Pos | NA | Neg | 16 | 0 | 10 | Not done | Pos++ | I–II | Yes | Yes | No | No | No |
3 | HBV | Pos | NA | Neg | 17 | 7 | 30 | IgG+, C3+,mesangial IgM+ | Pos+++ | I–IV | Yes | Yes | No | Yes | No |
4 | HBV | Pos | NA | Neg | 15 | 2 | 10 | IgG+ IgM+/−, C3 trace, IgA and C1q: negative | Pos+++ | II | Yes | No | Yes | Yes | Yes |
5 | HBV | Neg | Pos | Neg | 21 | 1 | 0 | IgG++ IgA+/− IgM+/− C3+/− C1q negative | Neg | I | Yes | No | Yes | Yes | Yes |
6 | HBV | Pos | NA | Neg | 25 | 0 | 0 | IgG++ IgM+/− C3+/− IgA and C1q: negative | Pos+++ | II | Yes | Yes | No | Yes | Yes |
7 | HCV | Pos | NA | NA | 18 | 1 | 15 | IgG++, mesangial IgM+, C1q++, C3+ | Pos+ | II | Yes | Yes | No | No | Yes |
8 | HCV | Pos | NA | NA | 16 | 2 | 5 | IgG++, IgM+/−,C3+ | Pos++ | I–II | Yes | Yes | No | Yes | No |
9 | HCV | Pos | NA | NA | 16 | 1 | 10 | IgG+++, C3++ | Pos++ | II | Yes | No | No | No | Yes |
10 | HCV | Neg | Neg | NA | 28 | 0 | 0 | IgG+ | Pos+ | II | Yes | Yes | No | Yes | No |
11 | HIV | Neg | NA | NA | 27 | 5 | 10 | IgG+, IgA+, IgM++, C3++ | NA | I–IV | Yes | Yes | Yes | Yes | No |
12 | HIV | Neg | Pos | NA | 23 | 2 | 5 | IgG+, IgM++, IgA Neg | NA | I–II | Yes | Yes | No | No | No |
13 | HIV | Neg | Neg | NA | 35 | 2 | 15 | IgG+, IgA+,IgM++ C1q+, C3++ | Neg | I–IV | Yes | Yes | No | Yes | No |
14 | HIV | Pos | NA | NA | 15 | 1 | 0 | IgG+, C3+ | Neg | I–IV | Yes | Yes | No | No | No |
15 | HIV | Neg | Pos | NA | 15 | 5 | 60 | IgG++, IgM++, C1q++, C3++ | Neg | II | Yes | Yes | No | Yes | No |
16 | HIV | Pos | NA | NA | 12 | 1 | 10 | IgA+ (segmental), IgG+++, IgM++, Mesangial IgA+, IgM+ | Pos ++ | III–IV | Yes | Yes | No | Yes | No |
17 | HIV HBV | Neg | Neg | Neg | 19 | 4 | 5 | IgG+, IgA++, C3+, C1q++, IgM+ mesangial IgM+ and C1q++ | Neg | II | Yes | No | Yes | No | No |
18 | HIV HBV | Pos | NA | Neg | 5 | 2 | 5 | IgG++, IgM+, segmental IgA+, C3+, C1q+ | NA | II | Yes | Yes | No | Yes | No |
19 | HIV HCV | Neg | Neg | NA | 24 | 3 | 5 | IgG+, scanty mesangial IgA+/−, IgM+/− C3+/− | Pos + | II | Yes | No | No | No | No |
IFTA: interstitial fibrosis and tubular atrophy; TRIs: tubuloreticular inclusions; NA: not available.