Concurrent medication: Children received disease-modifying antirheumatic drugs (DMARDs), [methotrexate (MTX), cyclosporine A (CSA), azathioprine (AZA)], biologicals [etanercept (ETA), tocilizumab (TCZ), adalimumab (ADA), rituximab (RTX)], nonsteroidal anti-inflammatory drugs (NSAIDs), and corticosteroids (CO).