Table 5.
Risk factors associated with abortion and macrosomia in patients with pregestational diabetes mellitus
| Variable | Abortion (N° = 12) |
No abortion (N° = 123) |
Crude OR (95% CI) |
Adjusted OR (95% CI) |
|---|---|---|---|---|
| Pregestational BMI | ||||
| ≤ 27.5 kg/m2 | 4 (31.7%) | 121 (98.3%) | 1 | 1 |
| > 27.5 kg/m2 | 8 (68.3%) | 2 (1.7%) | 3.76 (1.46–6.54) | 2.06 (1.01–4.22) |
| ∆_insulin requirement 1st trimester | ||||
| ≤ 0.27 | 3 (25%) | 101 (82.1%) | 1 | 1 |
| > 0.27 | 9 (75%) | 22 (17.9%) | 4.37 (1.61–11.8) | 2.02 (1.08–4.02) |
| Type 2 diabetes mellitus | ||||
| No | 3 (25%) | 70 (56.9%) | 1 | 1 |
| Yes | 9 (75%) | 53 (43.1%) | 11.5 (4.37–30.4) | 3.03 (1.29–7.10) |
|
Macrosomia (N° = 52) |
No macrosomia (N° = 83) |
|||
| Weight gain | ||||
| ≤ 12.5 kg | 10 (19.3%) | 65 (78.3%) | 1 | 1 |
| > 12.5 kg | 42 (80.7%) | 18 (21.7%) | 4.74 (1.86–12.1) | 2.36 (1.44–3.87) |
| ∆_insulin requirement 3rd trimester | ||||
| ≤ 0.07 | 22 (42.3%) | 60 (72.3%) | 1 | |
| > 0.07 | 30 (57.7%) | 23 (27.7%) | 1.25 (1–2.34) | |
| HbA1c of 3rd trimester | ||||
| ≤ 6.88 | 24 (46.2%) | 57 (68.7%) | 1 | |
| > 6.88 | 28 (53.8%) | 26 (31.3%) | 1.18 (1–2.09) | |
| Type 1 diabetes mellitus | ||||
| No | 17 (32.7%) | 45 (54.3%) | 1 | 1 |
| Yes | 35 (67.3%) | 38 (45.7%) | 12.3 (3.84–39.3) | 2.65 (1.14–3.98) |
Abbreviations: OR odds ratio, IC confidence interval