Table 1.
Treatment (mg/kg) | Percent increase in body weight | Absolute liver weight (g) | Relative liver weight (% to body weight) | Absolute kidney weight (g) | Relative kidney weight (% to body weight) |
---|---|---|---|---|---|
Normal control | 34.70 ± 1.82 | 5.28 ± 0.94 | 0.052 ± 0.001 | 1.56 ± 0.04 | 0.015 ± 0.0001 |
Diabetic control | 20.76 ± 1.21* | 3.42 ± 0.68 | 0.034 ± 0.001* | 0.42 ± 0.01 | 0.004 ± 0.0001* |
Db + PAB 200 | 25.29 ± 0.56*# | 4.12 ± 0.54 | 0.041 ± 0.001*# | 0.83 ± 0.08 | 0.008 ± 0.0001*# |
Db + PAB 400 | 28.98 ± 1.26*# | 4.88 ± 0.37 | 0.048 ± 0.002*# | 1.32 ± 0.02 | 0.013 ± 0.0003# |
Db + Glib 10 | 31.06 ± 0.98*# | 5.13 ± 0.75 | 0.051 ± 0.002# | 1.51 ± 0.02 | 0.015 ± 0.0002# |
Values are expressed as mean ± SEM (06). “*” indicates significance difference from normal control whereas “#” from diabetic control at P < 0.01 level
Db diabetic, PAB P. aphylla n-butanol extract, Glib glibenclamide