Figure 2.

The network modelling methods applied to meta-omics data. Various approaches have been proposed to construct network models based on different types of microbial meta-omics data. From metagenomics, the taxonomic and underlying functional profiling can be inferred, and we can construct co-occurrence networks and genome-scale metabolic networks, respectively. From metatranscriptomics, not only can we construct co-occurrence and genome-scale metabolic networks, but also construct regulatory networks. Additionally, we can construct PPI networks and metabolomics-driven metabolic networks based on metaproteomics and metabolomics, respectively.