Table 1.
Ionic concentrations of intracellular and extracellular media used to determine I Nab ionic selectivity
| Intracellular media | d‐Gluconic acid (sodium salt) (mM) | d‐Gluconic acid (potassium salt) (mM) | NaCl (mM) | KCl (mM) |
|---|---|---|---|---|
| [K+]i = 25 mM | 75 | 0 | 50 | 25 |
| [K+]i = 50 mM | 75 | 0 | 25 | 50 |
| [K+]i = 130 mM | 10 | 75 | 10 | 55 |
| [K+]i = 140 mM, with regular Na+ | 0 | 140 | 10 | 0 |
| [K+]i = 140 mM, with low Na+ | 0 | 140 | 0.5 | 0 |
| Extracellular media | d‐Gluconic acid (sodium salt) (mM) | NaCl (mM) | KCl (mM) | NMDG (mM) |
|---|---|---|---|---|
| control | 47.9 | 72.5 | 2.5 | 0 |
| low [Na+] | 0 | 15 | 2.5 | 105.4 |
Note that NaHCO3 and NaH NaH2PO4 concentrations remained constant at 26 mM and 1.1 mM, respectively.