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. 2021 Mar 4;11:559382. doi: 10.3389/fimmu.2020.559382

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Copyright © 2021 Kingstad-Bakke, Toy, Lee, Pradhan, Vogel, Marinaik, Larsen, Gates, Luu, Pandey, Kawaoka, Roy and Suresh

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Murine BMDC response to Adjuplex and TLR agonist-loaded PLP adjuvants. Murine BMDCs were treated with Adjuplex (ADJ) and/or PLPs with CpG, MPLA or GLA. (A) IFN-β response from BMDCs after 24 h of treatment with ADJ and/or PLP-CpG or PLP-MPLA. (B, C) IL-1β response from BMDCs after 24 h of treatment with ADJ and/or PLP-CpG, PLP-MPLA or PLP-GLA. Data are representative of two independent experiments. *, and **** indicate significance at P<0.1 and 0.0001 respectively.