Table 2.

Overall quality of the selected studies. Detailed description of the evaluated parameters is found in Table S4 .

Critical analysis of the articles included
Author	Year	Methodology											Toxicity		Outcomes		Score	Classification
		1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	%
Abd-Ellatef et al. (38)	2020																93	High quality
Alizadeh et al. (28)	2015																80	High quality
Chen et al. (26)	2017																93	High quality
Greish et al. (44)	2018																73	High quality
He et al. (36)	2019																86	High quality
Huang et al. (48)	2020																66	Moderate quality
Ji et al. (35)	2020																86	High quality
Jin et al. (37)	2017																86	High quality
Jung et al. (29)	2018												-	-			86	High quality
Kundu et al. (40)	2019																80	High quality
Laha et al. (31)	2019																73	High quality
Li et al. (39)	2018																86	High quality
Lin et al. (50)	2016																80	High quality
Lv et al. (41)	2015																60	Moderate quality
Mahalunkar et al. (27)	2019												-	-			86	High quality
Murkerjee et al. (45)	2016												-	-			73	High quality
Mukhopadhyay et al. (46)	2020																80	High quality
Sahne et al. (34)	2019																93	High quality
Shiri et al. (49)	2015												-	-			53	Moderate quality
Shukla et al. (25)	2017																86	High quality
Vaklinezhad et al. (32)	2019												-	-			73	High quality
Wang et al. (30)	2018												-	-			86	High quality
Yang et al. (42)	2017a																86	High quality
Yang et al. (43)	2017b																80	High quality
Yu et al. (47)	2014																80	High quality
Yuan et al. (33)	2018																86	High quality

Yes No Unclear - Not evaluated.