. 2021 Jan 17;24(3):300–313. doi: 10.1111/1756-185X.14060

TABLE 1.

The basic information of included studies in this meta‐analysis

Study	Y	Ethnicity	Polymorphisms	Sample size		Genotypes						Allele frequencies (%)
				Sample size		Control			Case			Control		Case
				Control	Case	CC	CT	TT	CC	CT	TT	C	T	C	T
Bhawna et al. ⁸	2005	Indian	rs5030737	119	120	104	15	0	100	20	0	93.7	6.3	91.7	8.3
Bhawna et al. ⁸	2005	Indian	rs5030737	145	120	132	13	0	100	20	0	95.5	4.5	91.7	8.3
Hou et al. ⁴⁷	2013	Chinese	rs5030737	378	280	362	15	0	278	2	0	97.9	2.1	99.6	0.4
Stanworth et al. ²⁰	1999	Caucasian	rs1800450	114	182	84	28	2	142	35	5	86.0	14.0	87.6	12.4
Ip et al. ⁴⁶	2000	Chinese	rs1800450	196	211	153	42	1	143	64	4	88.8	11.2	82.9	17.1
Horiuchi et al. ¹⁸	2000	Japanese	rs1800450	105	59	66	29	10	42	13	4	76.7	23.3	82.2	17.8
Tsutsumi et al. ⁵³	2001	Japanese	rs1800450	129	95	88	39	2	58	32	5	83.3	16.7	77.9	22.1
Bhawna et al. ⁸	2005	Indian	rs1800450	119	120	72	47	0	106	14	0	80.3	19.7	94.2	5.8
Bhawna et al. ⁸	2005	Indian	rs1800450	145	120	94	49	2	106	14	0	81.7	18.3	94.2	5.8
Min et al. ⁴⁹	2006	Chinese	rs1800450	48	93	36	12	0	66	24	3	87.5	12.5	83.9	16.1
Hou et al. ⁴⁷	2013	Chinese	rs1800450	378	280	231	138	10	195	76	9	79.2	20.8	83.2	16.8
Isabela et al. ¹⁶	2014	Brazilian	rs1800450	200	156	148	45	7	96	55	5	85.3	14.7	79.2	20.8
Isabela et al. ¹⁶	2014	Brazilian	rs1800450	120	156	79	41	0	96	55	5	82.9	17.1	79.2	20.8
Bhawna et al. ⁸	2005	Indian	rs1800451	119	120	111	8	0	110	10	0	96.6	3.4	95.8	4.2
Bhawna et al. ⁸	2005	Indian	rs1800451	145	120	129	16	0	110	10	0	94.5	5.5	95.8	4.2
Ip et al. ⁴⁶	2000	Chinese	rs7096206	174	115	119	50	5	68	41	6	82.8	17.2	76.5	23.5
Bhawna et al. ⁸	2005	Indian	rs7096206	119	120	70	43	6	60	50	10	76.9	23.1	70.8	29.2
Bhawna et al. ⁸	2005	Indian	rs7096206	90	120	46	32	12	60	50	10	68.9	31.1	70.8	29.2
Min et al. ⁴⁹	2006	Chinese	rs7096206	48	50	38	9	1	33	15	2	88.5	11.5	81.0	19.0
Isabela et al. ¹⁶	2014	Brazilian	rs7096206	200	156	130	58	12	109	38	9	79.5	20.5	82.1	18.9
Isabela et al. ¹⁶	2014	Brazilian	rs7096206	120	156	91	28	1	109	38	9	87.5	12.5	82.1	17.9
Hou et al. ¹⁷	2020	Chinese	rs7096206	400	380	232	160	8	230	143	7	77.9	22.1	79.3	20.7
Ip et al. ⁴⁶	2000	Chinese	rs11003125	174	115	48	87	39	20	56	39	52.6	47.4	41.7	58.3
Bhawna et al ⁸	2005	Indian	rs11003125	119	120	16	54	49	15	54	51	36.1	63.9	35.0	65.0
Bhawna et al. ⁸	2005	Indian	rs11003125	100	120	17	42	41	15	54	51	38.0	62.0	35.0	65.0
Min et al. ⁴⁹	2006	Chinese	rs11003125	48	50	17	23	8	15	25	10	59.4	40.6	54.0	46.0
Hou et al. ¹⁷	2020	Chinese	rs11003125	400	380	111	225	64	100	181	99	56.0	44.0	50.2	49.8
Jacobsen et al. ⁵¹	2000	Caucasian	MBL‐A/O	250	68	157	86	7	35	28	5	80.0	20.0	72.1	27.9
Koert et al. ⁴⁵	2008	Caucasian	MBL‐A/O	194	218	120	65	9	128	81	9	78.6	21.4	77.3	22.7
Fernanda et al. ¹⁹	2012	Brazilian	MBL‐A/O	345	322	207	120	18	171	131	20	77.4	22.6	73.4	26.6
Fernanda et al. ¹⁹	2012	Brazilian	MBL‐A/O	244	300	148	83	13	160	123	17	77.7	22.3	73.8	26.2
Fernanda et al. ¹⁹	2012	Brazilian	MBL‐A/O	101	22	59	37	5	11	8	3	76.7	23.3	68.2	31.8
Isabela et al. ¹⁶	2014	Brazilian	MBL‐A/O	200	156	119	73	8	75	73	8	77.8	22.2	71.4	28.6
Isabela et al. ¹⁶	2014	Brazilian	MBL‐A/O	120	156	62	58	0	75	73	8	75.8	24.2	71.4	28.6
Malthe et al. ⁴⁸	2014	Caucasian	MBL‐A/O	383	301	159	193	31	130	143	28	66.7	33.3	66.9	33.1
Malthe et al. ⁴⁸	2014	Caucasian	MBL‐YA/O	374	315	150	193	31	144	143	28	65.9	34.1	68.4	31.6

C, represent wild‐type allele; T, represent minor allele; MBL‐A/O, the presence of any of rs5030737, rs1800450, rs1800451 has been collectively labeled O, while the simultaneous absence of variants at the 3 positions has been called allele A, the wild‐type allele; MBL‐YA/O, the MBL‐A/O and presence of rs7096206.