Table 3.

C-indices with 95% CI for the ABC-AF-bleeding risk score in ARISTOTLE and RE-LY comparing geographic regions

	ARISTOTLE		RE-LY
	C-index	95% CI	C-index	95% CI
Major bleeding
All	0.677	0.657 to 0.698	0.708	0.684 to 0.731
Asia/Pacific	0.684	0.639 to 0.728	0.649	0.558 to 0.739
Europe	0.680	0.641 to 0.719	0.701	0.664 to 0.739
Latin America	0.674	0.629 to 0.719	0.657	0.561 to 0.754
North America	0.659	0.620 to 0.699	0.710	0.672 to 0.749
Other			0.760	0.698 to 0.822

ABC-AF bleeding score, Age, Biomarkers (troponin T-hs, haemoglobin, and GDF-15), Clinical history (previous bleeding); ARISTOTLE, Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation; RE-LY, Randomized Evaluation of Long-Term Anticoagulation Therapy.