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. 2021 Mar 22;14(3):e240283. doi: 10.1136/bcr-2020-240283

Table 1.

Individual scores on energy, pain and concentration as cognitive–behavioural therapy techniques are potentiated with modafinil in refractory chronic fatigue syndrome

Energy* Pain* Concentration* Modafinil
dosage (daily)
Social recovery
Baseline 4–6 months 10–12 months Baseline 4–6 months 10–12 months Baseline 4–6 months 10–12 months Baseline 4–6 months 10–12 months
Case 1 4.5 7.0 8.5 5.5 2.5 1.5 2.0 5.0 7.0 100 mg 300 mg 300 mg Returned to work
Case 2 4.5 5.0 5.0 5.0 7.0 7.0 6.0 6.0 6.5 100 mg 200 mg 200 mg Returned to work in a different post.
Case 3 3.5 6.0 6.5 6.5 0 2.0 6.5 6.5 6.5 25 mg increased to 50 mg in 2 weeks 50 mg 50 mg Returned to full-time training.

*Numbers represent ratings on a 0–10 scale, with 0=none and 10=highest energy, pain or concentration, respectively.