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. Author manuscript; available in PMC: 2021 Mar 23.
Published in final edited form as: Chem Res Toxicol. 2015 Nov 24;28(12):2352–2363. doi: 10.1021/acs.chemrestox.5b00359

Table 4.

Quantities (mol/g of Tissue) of Normal and Oxidized Pyrimidines in a Rat Brain Extract Measured Using Isotope-Labeled Standardsa

compound moles of free bases/g of tissue
uracil 1.20 ± 0.11 × 10−08
thymine 9.01 ± 0.46 × 10−10
cytosine 1.18 ± 0.15 × 10−09
5-methylcytosine 2.90 ± 0.13 × 10−11
5-formylcytosine 1.21 ± 0.15 × 10−09
5-hydroxymethyluracil 6.58 ± 0.37 × 10−11
5-carboxyuracil 8.76 ± 0.05 × 10−10
6-carboxyuracil 7.11 ± 0.08 × 10−10
5-hydroxymethylcytosine 7.77 ± 0.10 × 10−11
5-carboxycytosine <1.14 × 10−13
a

The data represent the average and standard deviation (SD) values from three different injections.