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[Preprint]. 2021 Jun 30:2021.03.11.435000. [Version 3] doi: 10.1101/2021.03.11.435000

Figure 5. Pulmonary effects of direct intranasal challenge with SARS-CoV-2 variant B.1.351 in Syrian hamsters at 5 DPI.

Figure 5.

a–b. H&E staining, 20x; a. No pathology. b. Focally extensive areas of bronchointerstitial pneumonia. c–d. H&E staining, 200x; c. No pathology. d. Bronchointerstitial pneumonia with alveolar histiocytosis, fibrin and edema. e–f. IHC staining against SARS-CoV-2 (brown). e. No staining. f. Staining of bronchiolar epithelial cells, type I&II pneumocytes and rare macrophages.