Table 1: Parameters for simulation scenarios.
Epidemic Model | ||
β | 0.003 – 0.009 | probability of transmission per 5-minute interaction* |
π ex | 0.002 | probability of external infection per day |
π ai | 0.3 | probability of asymp. infection15 |
|I0| | 1 | number of initial infections |
σ a | 1/3 | transition probability: exposed to asymp. infectious16 |
σ s | 1/3 | transition probability: exposed to symp. infectious16 |
γ a | 1/7 | transition probability: asymp. infectious to recovered17 |
γ s | 1/12 | transition probability: symp. infectious to recovered17 |
Testing | ||
π se | 0 – 0.96 | sensitivity, time-varying*18 |
π sp | 0.99 | specificity20 |
π sy | 1 day | delay between symptom onset and symp. testing |
π sc | 0.01 | probability non-compliant with scheduled testing |
π sy | 0.25 | probability non-compliant with symp. testing |
π fs | 0.005 | probability non-infectious present for symp. testing |
Isolation | ||
τ id | 1 day | delay between testing and entering isolation |
τ ic | Beta(5, 0.5) | isolation compliance |
τ ip | 10 days | isolation period21 |
Transmission Mitigation | ||
η fm | 0.15 | reduction in transmission probability for mask wearing22 |
η sd | 0.18 | reduction in transmission probability for social distancing22 |
π fm | 0–1 | proportion of the population wearing face masks* |
π sd | 0–1 | proportion of the population social distancing* |
π im | 0 – 0.4 | proportion of the population immune* |
Transmission probabilities, proportion of the population wearing face masks, proportion of the population social distancing, and proportion of the population immune varied across simulations. Test sensitivity was time-varying. An overview of the epidemic model is shown in Figure 2. For additional details on parameter values, see the corresponding sections of the Methods.