Skip to main content
. 2021 Mar 23;16(3):e0249003. doi: 10.1371/journal.pone.0249003

Table 2. Univariate analysis of factors for overall survival.

Variables N OS at 5 years (%) P value
Gender Male 30 0.598 0.979
Female 13 0.673
Age ≤ 70 year 19 0.648 0.256
> 70 year 24 0.609
Hepatitis B virus No 20 0.693 0.764
Yes 23 0.609
Hepatitis C virus No 28 0.567 0.699
Yes 15 0.733
Hypertension No 22 0.671 0.754
Yes 21 0.595
Diabetes mellitus No 31 0.641 0.578
Yes 12 0.635
Coronary artery disease No 36 0.850 0.286
Yes 7 0.833
Liver cirrhosis No 1 1.000 0.539
Yes 42 0.626
Child-Pugh Classification A 40 0.669 0.022
B 3 0
AJCC I-II 34 0.592 0.529
III 9 0.778
Number of tumors Single 33 0.603 0.915
Multiple 10 0.700
Tumor size < 5 cm 31 0.668 0.140
≥ 5 cm 12 0.571
Portal vein thrombosis Absent 35 0.650 0.511
Present 8 0.583
Hepatic vein thrombosis Absent 40 0.628 0.866
Present 3 0.667
Bile duct dilatation Absent 37 0.643 0.724
Present 6 0.625
Local tumor control Yes 40 0.683 < 0.001
No 3 0
Complete response CR 25 0.918 < 0.001
Non-CR 18 0
Early tumor regression ETR 22 0.856 0.014
No-ETR 21 0.381

AJCC: American Joint Committee on Cancer 8th edition; CR: complete response; ETR: early tumor regression; GyE: Gray equivalents; OS: overall survival.