Table 3. Summary of cellular and gene expression changes in patient subsets in GSE47460.

Subset in GSE47460	Associated cluster-specific cell type changes	Example gene expression changes
Subset 1.	Myeloid cell populations↑, mast cells↑, CTHRC1+ fibroblasts↑, pericytes↑, Alveolar fibroblasts subtypes↑	CCR2↑, CD11b↑, PPBP↑↑
Subset 2.	B cells/Plasma cells↑↑, Ciliated epithelium↑↑, Peribronchial fibroblasts↑, CTHRC1+ fibroblasts↑	MZB1↑, POU2AF1↑, FOXJ1↑↑

Column 2: ↑, moderately increased, ↑↑, strongly increased; Column 3: ↑, moderately upregulated over healthy (1.5-2x); ↑↑, strongly upregulated over healthy (>2x).