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. 2021 Mar 23;16(3):e0248853. doi: 10.1371/journal.pone.0248853

Table 2. Glycemic measures at the time of biomarker collection.

Variable Entire Cohort Euglycemia Hyperglycemia p value Hypoglycemia Both Hyperglycemia and Hypoglycemia
Plasma Glucose (mg/dL) 118 (88–153) 96 (81–124) 146 (117–218) 0.002 77 (56–82) 124 (73–133)
Plasma Insulin (μIU/mL) 9.8 (5.4–19.7) 8.1 (5.3–13.6) 12.9 (6.8–29.6) 0.005 7.8 (5.6–17.6) 5.4 (2.2–10.7)
Plasma C-Peptide (pg/mL) 2375 (1270–4442) 2151 (1349–3767) 2880 (1586–6916) 0.070 1969 (1723–3912) 428 (241–928)
HOMA-IR 2.7 (1.4–6.5) 1.8 (1.1–3.6) 5.7 (2.2–12.4) 0.002 1.5 (1.1–2.4) 1.9 (0.4–3.4)

Data are presented as median (interquartile range). p-values are for differences between euglycemia and hyperglycemia groups by rank sum test and are adjusted for multiple comparisons. Abbreviations: IU- international units; HOMA- homeostatic model-assessment of insulin resistance.