Table 1. Demographics and baseline characteristics of all subjects.
| Healthy subjects | POAG | NTG | Glaucoma | All | |||
|---|---|---|---|---|---|---|---|
| Count (%) | Diagnosis | 4 (50) | 2 (25) | 2 (25) | 4 (50) | 8 (100) | |
| Gender | F | 3 (60) | 0 (0) | 2 (40) | 2 (40) | 5 (62.5) | |
| M | 1 (33.3) | 2 (66.6) | 0 (0) | 2 (66.6) | 3 (37.5) | ||
| Study eye | L | 2 (66.6) | 0 (0) | 1 (33.3) | 1 (33.3) | 3 (37.5) | |
| R | 2 (40) | 2 (40) | 1 (20) | 3 (60) | 5 (62.5) | ||
| Mean ± SD | Age (y) | 42.7 ± 9.4 | 48.5 ± 12.0 | 77.5 ± 2.12 | 63.0 ± 18.2 | 52.9 ± 17.2 | |
| BMI (kg/m2) | 24.0 ± 7.3 | 27.0 ± 1.4 | 26.0 ± 5.6 | 26.5 ± 3.4 | 25.2 ± 5.5 | ||
| VF MD (dB) | -0.2 ± 0.8 | 0.3 ± 1.1 | -7.3 ± 8.3 | -3.5 ± 6.5 | -1.8 ± 4.7 | ||
| OCT RNFL (μm) | 97.7 ± 20.3 | 77.5 ± 17.5 | 76.0 ± 17.7 | 76.7 ± 11.3 | 87.2 ± 18.9 | ||
| Axial length (mm) | 23.8 ± 0.4 | 24.6 ± 0.5 | 22.7 ± 0.0 | 23.6 ± 1.1 | 23.7 ± 0.8 | ||
| Refraction (D) | Sph | -0.9 ± 1.3 | 0.2 ± 0.9 | 1.1 ± 0.0 | 0.7 ± 0.7 | -0.1 ± 1.3 | |
| Cyl | -1.1 ± 1.3 | -0.4 ± 0.1 | -1.2 ± 0.8 | -0.8 ± 0.6 | -1.0 ± 1.0 | ||
| corneal epithelial thickness (μm) | 50.2 ±2.9 | 47.5 ± 0.7 | 41.5 ± 0.7 | 44.5 ± 3.5 | 47.4 ± 4.3 | ||
| CCT (μm) | 541.7 ± 12.5 | 549.0 ± 22.6 | 518.5 ± 12.0 | 533.7 ± 23.0 | 537.7 ± 17.7 | ||
| CCR (mm) | 7.6 ± 0.1 | 7.9 ± 0.0 | 7.5 ± 0.0 | 7.7 ± 0.2 | 7.7 ± 0.1 | ||
| Corneal biomechanics | CH | 12.2 ± 1.3 | 9.0 ± 1.9 | 10.1 ± 1.5 | 9.6 ± 1.5 | 10.9 ± 1.9 | |
| CRF | 12.5 ± 1.8 | 13.5 ± 0.3 | 9.8 ± 0.9 | 11.7 ±2.2 | 12.1 ± 1.9 | ||
| IOPcc (mmHg) | 15.5 ± 3.8 | 29.7 ± 7.6 | 16.3 ± 3.8 | 23.0 ± 9.1 | 19.2 ± 7.6* | ||
| IOPg (mmHg) | 17.2 ± 4.2 | 29.7 ± 6.4 | 15.4 ±2.3 | 22.5 ± 9.2 | 19.9 ± 7.2* | ||
| IOPGAT (mmHg) | 15.8 ± 3.9 | 24.5 ± 2.1 | 17.0 ± 0.0 | 20.7 ± 4.5 | 18.3 ± 4.7* | ||
| IOPPneumatonometer (mmHg) | 20.5 ± 4.2 | 29.4 ± 7.2 | 21.8 ± 0.0 | 25.6 ±6.1 | 23.0 ± 5.6* | ||
*p-value resulting from a Kruskal-Wallis test did not show any significant difference between tonometers.
SD: standard deviation; POAG: Primary open angle glaucoma; NTG: Normal tension glaucoma; F: female; M: male; L: left; R: right; y: years; VF MD: visual field mean deviation; dB: decibel; OCT RNFL: Optical coherence tomography retina nerve fiber layer; Sph: spherical; Cyl: cylinder; CCT: central corneal thickness; CCR: central corneal radius; CH: corneal hysteresis; CRF: corneal resistance factor.