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. 2021 Mar 2;17(3):e1009301. doi: 10.1371/journal.ppat.1009301

Table 2. Details of nuclear encoded complex III subunits.

Phenotype scores were taken from Sidik et al., 2016 [56]; Matrix proteome from Seidi et al., 2018 [7]; (Y–present in proteome, N–absent); LOPIT from Barylyuk et al., 2020 [36] (mm–mitochondrial membrane, N/A–not identified in dataset). TMD: Transmembrane domain, predicted by TMHMM server. TGGT1_297160 was initially identified as a potential complex III subunit but was later excluded.

Gene ID Name Human/yeast homolog Phenotype score Matrix proteome LOPIT Length (aa) TMD (TMHMM)
TGGT1_246540 CytC1 CYC1/CYT1 -4.36 Y mm 398 Yes (1)
TGGT1_320220 Rieske UQCRFS1/RIP1 -5.76 Y mm 487 No
TGGT1_236210 QCR1 UQCRC1/QCR1 -4.74 Y mm 509 No
TGGT1_202680 QCR2 UQCRC2/QCR2 -4.3 Y mm 563 No
TGGT1_320140 QCR6 UQCRH/QCR6 -3.69 Y mm 89 No
TGGT1_288750 QCR7 UQCRB/QCR7 -4.04 Y mm 234 No
TGGT1_227910 QCR8 UQCRQ/QCR8 -3.2 Y mm 122 No
TGGT1_201880 QCR9 UQCR10/QCR9 -3.63 Y mm 128 No
TGGT1_214250 QCR11 - -3.94 Y mm + o 80 Yes (1)
TGGT1_207170 QCR12 - -3.44 Y mm 141 Yes (1)
TGGT1_297160 - - 0.1 Y mm 564 No