Table 2. Plasma concentrations of cytokines in control, CD, and DCM groups expressed as mean ± standard error of the mean (SEM).
| Cytokines | Control | CD 0 | CD I-II | CD III-IV | DCM I-II | DCM III-IV | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | |
| IL-1alpha | 14.63 | 3.85 | 15.38 | 2.89 | 16.19 | 4.15 | 12.71 | 3.57 | 13.78 | 3.82 | 13.79 | 5.12 |
| IL-16 | 319.6 | 28.9 | 309.7 | 19.1 | 322.5 | 19.2 | 344.6 | 30.2 | 374.9 | 30.8 | 354.8 | 22.3 |
| IL-18 | 139.1 | 22.2 | 146.2 | 21.3 | 134.4 | 20.6 | 171.2 | 28.6 | 182.9 | 31.9 | 157.5 | 30.2 |
| M-CSF | 28.02 | 5.25 | 24.71 | 4.29 | 28.01 | 4.86 | 35.55 | 6.82 | 27.22 | 6.69 | 26.97 | 5.45 |
| MIF | 162.9 | 19.2 | 206.1 | 24.3 | 189.3 | 26.3 | 324.5* | 64.5 | 171.0 | 21.6 | 196.9 | 20.7 |
| SCF | 195.0 | 18.5 | 196.0 | 16.6 | 201.5 | 20.9 | 223.1 | 26.9 | 219.9 | 26.1 | 228.4 | 23.0 |
| SCGF beta | 24,130 | 4856 | 22,943 | 2,638 | 26,103 | 5,226 | 46,231# | 9,495 | 28,944 | 6,168 | 45,903# | 7,705 |
| TNF | 17.04 | 3.29 | 14.88 | 2.33 | 15.35 | 2.87 | 12.90 | 2.44 | 18.48 | 3.79 | 14.62 | 4.15 |
| TRAIL | 148.0 | 16.9 | 152.7 | 11.3 | 182.9 | 24.8 | 192.3 | 26.1 | 170.0 | 21.8 | 186.1 | 28.5 |
| IL-12p40 | 130.6 | 19.7 | 171.9 | 17.2 | 178.5 | 27.7 | 260.3 | 50.4 | 172.0 | 26.5 | 246.0 | 41.8 |
| IL-2R alpha | 100.9 | 10.3 | 102.7 | 7.30 | 104.6 | 12.3 | 123.0 | 16.0 | 95.63 | 7.60 | 125.1 | 12.5 |
| IL-3 | 73.29 | 8.88 | 82.60 | 7.43 | 79.53 | 8.00 | 91.00 | 10.3 | 84.69 | 9.15 | 98.01 | 9.56 |
| HGF | 240.2 | 27.4 | 242.5 | 16.9 | 284.0 | 36.5 | 649.0***/### | 91.4 | 321.4 | 30.8 | 550.5***/### | 54.9 |
| IFN-alpha2 | 57.79 | 4.08 | 57.73 | 3.09 | 58.36 | 3.91 | 63.97 | 5.43 | 61.84 | 3.95 | 69.96 | 3.48 |
| beta-NGF | 18.30 | 4.13 | 16.28 | 2.62 | 19.91 | 4.38 | 22.51 | 4.44 | 22.44 | 5.60 | 26.23 | 5.87 |
| LIF | 76.14 | 4.10 | 51.46 | 7.56 | 53.96 | 9.15 | 44.19 | 9.09 | 54.69 | 11.1 | 56.71 | 10.8 |
| CCL27 | 1,436 | 77.0 | 1,317 | 70.0 | 1,519 | 121 | 1,798# | 220 | 1,504 | 101 | 1,480 | 101 |
| CXCL1 | 45.48 | 8.95 | 42.44 | 6.22 | 48.10 | 6.13 | 56.01 | 7.87 | 39.94 | 4.87 | 42.47 | 4.87 |
| CCL7 | 19.74 | 3.74 | 17.26 | 1.46 | 15.96 | 2.10 | 24.72 | 4.90 | 15.75 | 2.85 | 23.65 | 3.20 |
| CXCL9 | 808.4 | 147 | 1,224 | 163 | 1,695 | 324 | 2,329***/$ $ | 412 | 832.8 | 95.3 | 1,307 | 211 |
| CXCL12 | 138.6 | 21.3 | 173.7 | 18.3 | 178.8 | 26.6 | 214.2 | 35.4 | 164.7 | 24.2 | 266.5* | 30.0 |
All values are expressed in picograms per milliliter (pg/mL).
*p< 0.05 vs control.
# p< 0.05 vs CD 0.
***p< 0.001 vs control.
###p< 0.001 vs CD 0.
$ $p< 0.01 vs DCM I-II.