. Author manuscript; available in PMC: 2022 Mar 1.

Published in final edited form as: Parkinsonism Relat Disord. 2021 Feb 10;84:105–111. doi: 10.1016/j.parkreldis.2021.02.006

Table 2.

Associations between mobility measures and PD outcomes

		MDS-UPDRS-Adjusted
Measure	MDS-UPDRS III	Cognition	Disability
32-ft. walk
Speed	−2.65 (0.0009)	0.38 (0.165)	2.31 (0.0002)^*
Cadence	−1.82 (0.026)	0.92 (0.0006)^*	1.11 (0.082)^*
Regularity	−0.50 (0.633)	0.83 (0.014)^*	−0.55 (0.488)
Stride variability	2.27 (0.002)	−0.44 (0.079)	−2.24 (0.0001)^*
TUG Sit to Stand (S1)
Anterior-Posterior	−0.99 (0.248)	0.07 (0.801)	0.68 (0.303)
Range	−1.54 (0.075)	0.24 (0.415)	0.86 (0.193)
Posterior	−3.09 (0.005)	0.006 (0.987)	2.43 (0.005)^*
TUG Stand to Sit (S2)
Jerk	−3.05 (0.002)	0.343 (0.306)	0.97 (0.215)^*
Range	0.25 (0.763)	0.08 (0.767)	0.37 (0.561)
TUG turning
Yaw	5.52 (1.6×10⁻⁸)	−0.13 (0.724)	−1.65 (0.053)^*
Frequency	−0.30 (0.729)	−0.36 (0.203)	−1.13 (0.079)
Standing posture
Sway	3.17 (0.0002)	−0.26 (0.398)	−1.99 (0.007)^*

Regression model Beta (p-value) shown for associations between each quantitative mobility measures and motor MDS-UPDRS score, as well as cognition, and disability. All models are adjusted for age, sex, disease duration, and the associations with cognition and physical functioning are additionally adjusted for motor MDS-UPDRS score. Significant associations are underlined. Asterisks indicate those measures that were significantly associated with either cognition or physical functioning in models adjusted for age, sex, and disease duration only (See Table S2). MDS-UPDRS= Movement Disorder Society-Unified Parkinson Disease Rating Scale; TUG=Timed Up and Go.