TABLE 1.
Baseline Patient Characteristics
| Variable | No Revascularization (n = 18,534) | Early Revascularization (n = 554) | p Value |
|---|---|---|---|
| Site | <0.001 | ||
| Assuta Medical Center | 7,363 (39.7) | 283 (51.1) | |
| Brigham and Women’s Hospital | 2,212 (11.9) | 49 (8.8) | |
| Cedars-Sinai Medical Center | 3,234 (17.5) | 78 (14.1) | |
| Oregon Heart and Vascular Institute | 2,536 (13.7) | 66 (11.9) | |
| Ottawa Heart Institute | 3,189 (17.2) | 78 (14.1) | |
| Demographic characteristics | |||
| Age, yrs | 63.8 ± 12.1 | 65.6 ± 10.6 | <0.001 |
| Male | 10,180 (54.9) | 445 (80.3) | <0.001 |
| BMI, kg/m2 | 28.4 ± 6.1 | 28.2 ± 4.3 | 0.264 |
| Cardiovascular risk factors | |||
| Peripheral vascular disease | 1,993 (10.8) | 72 (13.0) | 0.096 |
| Hypertension | 11,542 (62.3) | 403 (72.7) | <0.001 |
| Diabetes mellitus | 4,541 (24.5) | 199 (35.9) | <0.001 |
| Hyperlipidemia | 11,474 (61.9) | 404 (72.9) | <0.001 |
| Family history of CAD | 5,153 (27.8) | 140 (25.3) | 0.194 |
| Smoking | 3,536 (19.1) | 91 (16.4) | 0.124 |
| Prior PCI | 3,197 (17.3) | 164 (29.6) | <0.001 |
| Typical angina | 992 (5.4) | 120 (21.7) | <0.001 |
| Stress test type | 0.003 | ||
| Exercise | 9,111 (49.2) | 237 (42.8) | |
| Pharmacological | 9,423 (50.8) | 317 (57.2) | |
| Stress ECG response | <0.001 | ||
| Negative | 16,755 (90.4) | 355 (64.1) | |
| Positive | 1,779 (9.6) | 199 (35.9) | |
| Myocardial perfusion study | |||
| Ejection fraction, % | 62.6 ± 11.2 | 56.5 ± 11.3 | <0.001 |
| Ischemic TPD | 2.4 ± 2.9 | 10.2 ± 7.1 | <0.001 |
| Ischemic TPD | <0.001 | ||
| 0% to 5% | 15,776 (75.5) | 154 (27.8) | |
| >5% to 10% | 2,226 (12.0) | 146 (26.4) | |
| >10% | 532 (2.9) | 254 (45.9) | |
| MACE | 1,770 (9.6) | 66 (11.9) | 0.067 |
Values are n (%) or mean ± SD.
BMI = body mass index; CAD = coronary artery disease; MACE = major adverse cardiovascular event(s); PCI = percutaneous coronary intervention; TPD = total perfusion deficit.