Table 2.
Lung Function After Bronchodilatation in COPD Patients Stratified by Exacerbation Rate
| Variable | Annual Exacerbation Rate 2 Years Prior to Index Date | |||
|---|---|---|---|---|
| 0 | 1 | ≥2 | ||
| FEV1 | Mean (95% CI) | 1.9 (1.8, 1.9) | 1.8 (1.7, 1.8) | 1.7 (1.7, 1.8) |
| N (%) | 2851 (35.2) | 1376 (33.6) | 1809 (28.3) | |
| FVC | Mean (95% CI) | 2.9 (2.8, 2.9) | 2.7 (2.7, 2.8) | 2.7 (2.7, 2.7) |
| N (%) | 2716 (33.6) | 1314 (32.1) | 1725 (27.0) | |
| FEV1/FCV ratio | Mean (95% CI) | 0.60 (0.59, 0.61) | 0.60 (0.59, 0.61) | 0.59 (0.58, 0.60) |
| N (%) | 2863 (35.4) | 1391 (34.0) | 1846 (28.8) | |
| FEV1% predicted | Mean (95% CI) | 65.1 (64.4, 65.8) | 63.1 (62.1, 64.1) | 61.4 (60.5, 62.2) |
| N (%) | 3307 (40.1) | 1651 (40.3) | 2193 (34.4) | |
| FVC % predicted | Mean (95% CI) | 76.7 (76.0, 77.4) | 74.4 (73.5, 75.4) | 73.4 (72.5, 74.2) |
| N (%) | 3079 (38.0) | 1537 (37.6) | 2014 (31.5) | |
Notes: Lung function values are the ones closest to (either before or after) index date. N (%) indicate the number of patients and (percent of patients in that group) in whom lung function measurement were available.
Abbreviations: CI, confidence interval; FEV1, forced expiratory volume in one second; FVC, forced vital capacity.