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. Author manuscript; available in PMC: 2021 Mar 23.
Published in final edited form as: Genet Epidemiol. 2020 Mar 1;44(5):442–468. doi: 10.1002/gepi.22288

FIGURE 2.

FIGURE 2

Conditional and joint analysis (COJO) for genes near a strong breast cancer GWAS hit. (a) COJO results adjusting for predicted expression of ALS2CR12. After conditioning on ALS2CR12, almost all original significant GWAS signals (grey dots) disappear (blue dots). (b) COJO results adjusting for the predicted expression of CASP8. After conditioning on CASP8, some of the original GWAS significant signals (grey dots) remains (blue dots)