hsCRP and outcome after TBI: (A) GOSE ≥5 versus <5 (B) GOSE = 8 versus <8. Line plots indicate median and 25th–75th percentile. (A) In patients with serial hsCRP samples (day 1 and 2 weeks, and day 3 and/or day 5), hsCRP level was compared between patients with unfavorable outcome (GOSE <5, indicating death/severe disability) and favorable outcome (GOSE ≥5). Patients with favorable outcome had significantly higher hsCRP level at all time points compared to patients with unfavorable outcome. (B) In patients with serial hsCRP samples, hsCRP level was compared between patients with complete recovery (GOSE = 8) and incomplete recovery (GOSE <8). Patients with incomplete recovery had significantly higher hsCRP level at the 2-week time point compared with patients with complete recovery, but were not significantly different at any other time point. GOSE, Glasgow Outcome Scale-Extended; hsCRP, high-sensitivity C-reactive protein; TBI, traumatic brain injury.