Figure 10.

BSYS regulated the expression of serum exosomal miR-124 and miR-155 in EAE mice. (a) Exosomes derived from mice serum were observed by transmission electron microscopy. (b) Exosome markers (CD63, HSP70, and TGS101) were detected by western blot. (c) Particle sizes of serum exosomes were measured by NTA. (d, e) The expression levels of miR-124 and miR-155 in serum exosomes from mice of each group were detected by qRT-PCR. Data are presented as means ± SD; compared with the NC group, ^##P < 0.01; compared with the EAE group, ^∗P < 0.05, ^∗∗P < 0.01.