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. 2021 Feb 11;15:1185. doi: 10.3332/ecancer.2021.1185

Table 4. Cox uni and multivariable logistic regression to evaluate factors associated with OS and metastases recurrence-free survival.

OS Metastases-free survival
Univariate Multivariable Univariate Multivariable
HR p HR p HR p HR p
Age at Dx 1.01 0.13 - - 0.99 0.45 - -
BMI 1.05 0.06 - - 1.03 0.21 - -
Clinical Stage (TNM)
I–II
III
-
3.55
-
<0.001a
-
3.05
-
0.001a
-
3.18
-
<0.001a
-
2.82
-
<0.0001a
Compromised LN (yes) 5.4 0.001a - - 2.80 0.003a - -
pCR 0.52 0.03a 0.69 0.009a 0.43 0.003a 0.48 0.02a
HR positive 0.62 0.02a - - 0.62 0.01a - -
HER2 positive 0.78 0.26 - - 0.70 0.08 - -
Subgroup by receptors
HR+/HER2−
HR+/HER2+
HR−/HER2+
HR−/HER2−
-
0.81
1.17
1.73
-
0.49
0.61
0.03a
-
1.40
1.34
2.56
-
0.33
0.42
0.001a
-
0.67
1.07
1.68
-
0.16
0.79
0.03a
-
1.04
1.60
2.63
0.89
0.14
<0.001a
FHx of cancer 0.72 0.18 - - 0.70 0.11 - -
NeoCT regime
Anthracyclines only
Taxanes only
Anthracyclines and Taxanes
-
0.18
0.38
-
0.09
<0.001a
-
0.29
0.55
-
0.23
0.03a
-
0.28
0.33
-
0.09
<0.001a
-
0.57
0.49
-
0.45
0.003a
Adjuvant radiotherapy 0.57 0.09 - - 0.63 0.17