Table 4.
Large artery distensibility and cardiovascular parameters at the different time points.
| Parameter | T0 (Baseline) | T3 (3 months) | T6 (6 months) |
|---|---|---|---|
| PWV (m/sec) | 13.1 ± 3.10 | 13.6 ± 3.08 | 14.4 ± 4.11 |
| AP (mm Hg) | 26.0 ± 13.5 | 29.8 ± 12.8 | 26.1 ± 15.9 |
| AP(75) (mm Hg) | 21.6 ± 9.42 | 25.8 ± 9.70 | 24.5 ±8.8 |
| Central SBP (mm Hg) | 129 ± 28.6 | 126 ± 13.8 | 132 ± 25.4 |
| Central DBP (mm Hg) | 81.7 ±13.8 | 80.1 ± 6.00 | 86 ± 11.7 |
| Central PP (mm Hg) | 47.5 ± 17.2 | 45.6 ± 9.64 | 46.5 ± 18.2 |
| Left ventricular hypertrophy (n, %) | 1/13, 7.7% | 1/10, 10% | 2/11, 18% |
| LVMI (g/m2) | 80.0 ± 19.0 | 85.3 ± 14.1 | 82.8 ± 18.2 |
| LVMh2.7 (g/m) | 36.0 ± 9.30 | 38.8 ± 7.98 | 36.6 ± 9.86 |
| Relative wall thickness | 0.37 ± 0.06 | 0.38 ± 0.02 | 0.37 ± 0.05 |
| Ejection fraction (%) | 60.6 ± 4.62 | 61.1 ± 5.22 | 69.7 ± 5.20 |
| Cardiac output (L/min) | 3.84 ± 1.32 | 3.63 ± 1.57 | 3.54 ± 1.22 |
| Cardiac index ((L/min/m2) | 1.06 ± 0.34 | 0.93 ± 0.28 | 0.93 ± 0.20 |
| e velocity (cm/sec) | 68.5 ± 19.2 | 65.5 ± 21.6 | 58.7 ± 21.5 |
| a velocity (cm/sec) | 91.5 ± 23.8 | 83.2± 31.1 | 72.4 ± 24.7 |
| e/a | 0.75 ± 0.11 | 0.88 ± 0.35 | 0.86 ± 0.28 |
| E-wave deceleration time (msec) | 222 ± 46.9 | 257 ± 40.1* | 240 ± 51.7# |
| IVRT (mm/sec) | 88.1 ± 9.9 | 96.6 ± 30.7 | 97.6 ± 13.0§ |
| Carotid artery intima/media thickening (n, %) | 12/13, 92% | NA | NA |
| CA MeanMax (mm) | 1.31 ± 0.30 | NA | NA |
| CB Max (mm) | 1.36 ± 0.33 | NA | NA |
AP, augmentation pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; LVMI, left ventricular mass index; LVMh, ventricular mass indexed for height; IVRT, isovolumic deceleration time; CA MeanMax, mean maximum intima-media thickness of internal, external carotid artery and bifurcation; CB Max, maximum intima-media thickness of external carotid artery and bifurcation; NA, not available.
T-student analysis:
*
T3 vs. T0 p = 0.04;
#
T6 vs. T0 p = 0.03;
§
T6 vs. T0 p = 0.01.