Typical Lipoprotein profiles of mice plasma. The apoA-I floxed (Apoa1fl/fl) mice without cre expression(A), with villin-cre expression, Apoa1ΔInt (B), with albumin-cre expression, Apoa1ΔLiv (C), with both villin-cre and albumin-cre expression, Apoa1ΔIntΔLiv (D), with CAG-cre expression, Apoa1/- (E), Abca1-null mice(F), and Lcat-null mice(G) plasma were analyzed by the gel-permeation HPLC equipped with an online enzymatic colorimetric lipid assay system (Skylight Biotech Inc, Japan). Solid burgundy line, total cholesterol. The dotted blue line, triacylglycerol. Solid triangles, open arrows, and solid arrows point to the typical retention time of human VLDL, human LDL, and human HDL, respectively.