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. 2021 Jan 31;11(2):373–395. doi: 10.1007/s13346-021-00918-5

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© The Author(s) 2021, corrected publication 2021

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Fig. 6 — Being able to fractionate complex mixtures, AF4 can characterize the transfer of small-molecule drugs to lipophilic scavengers such as albumin a or lipoproteins b. AF4 can also help to differentiate whether the release happens as a consequence of carrier disruption c or drug diffusion d