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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Curr Opin Microbiol. 2021 Feb 15;60:51–57. doi: 10.1016/j.mib.2021.01.006

Figure 1: The Gram-negative cell envelope and LPS transport.

Figure 1:

A) Structure of LPS from Escherichia coli K-12. B) ATP utilization by LptB2FGC drives the transport of newly synthesized LPS (yellow) across the periplasmic compartment. LptB2FGC is depicted both as a crystal structure (PDB ID: 6MJP) derived from Vibrio cholerae (left) and as a cartoon (right). The crystal structure carries the catalytically inactive LptB/E163Q variant. LPS, lipopolysaccharide. PL, phospholipid. PG, peptidoglycan. OM, outer membrane. IM, inner membrane. Peri, periplasm. Kdo, keto-deoxyoctulosonate. Hep, heptose. Glu, glucose. Gal, galactose.