Table 4.
Lung function parameters.
| Controls n = 125 | GLILD n = 47 | uILD n = 26 | p value | p value | p value | |
|---|---|---|---|---|---|---|
| Median (IQR) | Median (IQR) | Median (IQR) | (GLILD vs. ctrls) | (uILD vs. GLILD) | (uILD vs. ctrls) | |
| FEV1 (% of predicted) | 102 (89–111) | 88 (72–105) | 103 (89–110) | 0.02 | 0.03 | 0.94 |
| 0.006 | 0.15 | 0.35 | ||||
| FVC (% of predicted) | 104 (92–116) | 88 (72–103) | 104 (93–113) | <0.001 | 0.01 | 0.72 |
| <0.001 | 0.01 | 0.40 | ||||
| TLC (% of predicted) | 102 (94–108) | 87 (75–102) | 93 (87–104) | <0.001 | 0.32 | 0.03 |
| 0.001 | 0.29 | 0.05 | ||||
| DLCO (% of predicted) | 83 (75–97) | 61 (52–80) | 73 (65–86) | <0.001 | 0.008 | 0.02 |
| <0.001 | 0.02 | 0.07 |
For each cell: Upper p-value from Wilcoxon-Mann-Whitney test. Lower p value from linear regression models adjusted for disease duration (difference between age at enrolment and age at CVID onset).