Table 5.
Univariate logistic regression analysis and area under ROC curve for different possible GLILD predictors.
GLILD vs. Controls | Odds Ratio | p value | AUC | |
---|---|---|---|---|
n | (95% C.I.) | |||
IgA at diagnosis (mg/dl) | 47 vs. 125 | 0.97 (0.95–0.99) | 0.008 | 0.65 |
IgG at diagnosis (mg/dl) | 47 vs. 125 | 0.997 (0.995–0.999) | 0.048 | 0.60 |
CD21lo B cells % | 29 vs. 100 | 1.099 (1.05–1.15) | <0.001 | 0.78 |
FVC (% of predicted) | 44 vs. 99 | 0.96 (0.94–0.98) | <0.001 | 0.71 |
DLCO (% of predicted) | 38 vs. 75 | 0.94 (0.91–0.96) | <0.001 | 0.80 |
TLC (% of predicted) | 34 vs. 64 | 0.95 (0.92–0.98) | 0.001 | 0.71 |
AI Cytopenia (ITP, AIHA) | 47 vs. 125 | 12.69 (5.60–28.77) | <0.001 | 0.75 |
ITP | 47 vs. 125 | 18.11 (7.23–45.37) | <0.001 | 0.74 |
Splenomegaly | 47 vs. 125 | 8.86 (3.68–21.36) | <0.001 | 0.73 |
n, number of observations. ITP, AIHA: history of ITP and/or AIHA.