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(A) TSA treatment-induced FAP BAT differentiation as evidenced by UCP-1(+) PDGFRα (+) BAT-FAPs (arrows) in SS muscle after TT + DN. (B) TSA increased HDAC activity in both supraspinatus (SS) and infraspinatus (IS) muscles after TT + DN (*p < .05). BAT, brown fat adipose tissue; DN, denervation transection; FAPs, fibro/adipogenic progenitors; TSA, Trichostatin A; TT, tendon transection; UCP-1, uncoupling protein-1
