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. 2021 Mar 10;11:639013. doi: 10.3389/fonc.2021.639013

Figure 1.

Figure 1

Single-cell profiling and cell-type identification in both healthy and BCP-ALL samples. (A) Distribution of 58,518 cells from 11 samples shown by uniform manifold approximation and projection (UMAP). (B) UMAP plot showing similar cell distributions in normal and tumor samples. (C) Gene expression heatmap of marker genes for the identification of six cell types. (D) UMAP visualization of six marker-based cell types. Cell types are colored as in (C). (E) Stacked barplots showing the frequencies of six cell types in all of the 11 samples. Cell types are colored as in (C). (F) Expression level of MME of B cells from normal and tumor samples. (G) Inferred CNV level of B cells from normal and tumor samples.