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. 2021 Mar 10;12:649079. doi: 10.3389/fneur.2021.649079

Table 1.

Clinical characteristics.

Characteristics All (%) EVF (%) EVF+ (%)
Number of patients 147 114 (77.6) 33 (22.4)
Age (average) 72.8 71.2 78
Female 101 (68.7) 79 (69.3) 22 (66.7)
Hypertension 105 (71.4) 79 (69.3) 26 (78.8)
Hypercholesterolemia 79 (53.7) 57 (50) 22 (66.7)
Diabetes 24 (16.3) 20 (17.5) 4 (12.1)
Coronary artery disease 43 (29.3) 33 (28.9) 10 (30.3)
Atrial fibrillation 66 (44.9) 48 (42.1) 18 (54.5)
Chronic kidney disease 24 (16.3) 17 (14.9) 7 (21.2)
Smoking (Prior/Active) 49 (33.3) 43 (37.7) 6 (18.2)
Prior stroke 18 (12.2) 14 (12.3) 4 (12.1)
Prior intracerebral hemorrhage 3 (2.0) 3 (2.6) 0 (0)
Anticoagulant/Antiplatelet therapy
Aspirin 48 (32.7) 39 (34.2) 9 (27.3)
Clopidogrel 7 (4.8) 6 (5.2) 1 (3.0)
Warfarin 13 (8.8) 10 (8.8) 3 (9.1)
Heparin 1 (0.7) 1 (0.9) 0 (0)
Direct oral anticoagulant 16 (10.9) 14 (12.3) 2 (6.1)
Baseline scores
Baseline NIHSS (average) 15.5 15.0 17.2
Baseline mRS (average) 0.5 0.5 0.5
Thrombolysis
IV tPA 36 (24.5) 26 (22.8) 10 (30.3)
Time to IV tPA (min), average 110 110 111
Occlusion site
Internal carotid artery 49 (33.3) 35 (30.7) 14 (42.4)
M1 81 (55.1) 66 (57.9) 15 (45.5)
M2 17 (11.6) 13 (11.4) 4 (12.1)
TICI score
2a 15 (10.2) 8 (7.0) 7 (21.2)
2b 52 (35.4) 41 (36.0) 11 (33.3)
3 80 (54.4) 65 (57.0) 15 (45.5)
Time to recanalisation (min), average 293 291 299
Post-treatment imaging modality
CT 145 (98.6) 113 (99.1) 32 (97.0)
MRI 93 (63.3) 70 (61.4) 23 (69.7)
Both 92 (62.3) 70 (61.4) 22 (66.7)
Reperfusion hemorrhage
Any hemorrhage 42 (28.6) 28 (24.6) 14 (42.4)
HI1 13 (8.8) 8 (7.0) 5 (15.2)
HI2 7 (4.8) 6 (5.3) 1 (3.0)
PH1 15 (10.2) 10 (8.8) 5 (15.2)
PH2 7 (4.8) 4 (3.5) 3 (9.1)

EVF, Early Venous Filling; NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin Scale; IV tPA, Intra-Venous tissue Plasminogen Activator; TICI, Thrombolysis in Cerebral Infarction; CT, Computed Tomography; MRI, Magnetic Resonance Imaging; HI, Hemorrhagic Infarction; PH, Parenchymal Hematoma.