Table 3.

Associations between T and NK cell concentrations in peripheral blood of healthy donors before and after G-CSF stimulation and corresponding concentrations in stem cell grafts, n=17.

Cell subset	Stem cell graft Concentration, 109/L median (IQR)	Correlation to pre-G-CSF concentrations, Rho/p-value	Fold increase to pre-G-CSF concentrations	Correlation to post-G-CSF concentrations, Rho/p-value	Fold increase to post-G-CSF concentrations
CD3	42 (30-59)	0.41/0.03	28	0.43/0.02	14
CD4	26 (20-26)	0.26/0.15	29	0.42/0.02	14
CD8	15 (9.4-22)	0.53/0.003	35	0.50/0.008	15
TCR γδ	0.98 (0.43-1.1)	0.71/<0.001	38	0.62/0.001	16
Vδ1	0.23 (0.11-0.39)	0.65/<0.001	29	0.60/0.001	15
Vδ2	0.34 (0.18-0.62)	0.57/0.001	18	0.73/<0.001	10
NonVδ1-nonVδ2	0.08 (0.04-0.11)	0.69/<0.001	44	0.82/<0.001	16
Naïve TCR γδ	0.04 (0.02-0.07)	0.78/<0.001	36	0.73/<0.001	15
Central memory TCR γδ	0.09 (0.02-0.14)	0.79/<0.001	30	0.72/<0.001	18
Effector memory TCR γδ	0.25 (0.15-0.41)	0.59/0.001	18	0.58/0.002	11
TEMRA γδ	0.37 (0.22-0.58)	0.71/<0.001	26	0.65/<0.001	13
Naive CD4	12 (8.9-19)	0.41/0.02	39	0.67/<0.001	14
Central memory CD4	9.8 (8.2-15)	0.49/0.007	30	0.43/0.02	15
Effector memory CD4	3.2 (1.9-4.8)	0.41/0.02	26	0.37/0.05	14
TEMRA CD4	0.13 (0.09-0.79)	0.62/0.001	37	0.67<0.001	8
Naive CD8	4.6 (2.9-6.0)	0.63/<0.001	56	0.55/0.003	17
Central memory CD8	1.1 (0.9-2.0)	0.41/0.02	23	0.45/0.02	17
Effector memory CD8	3.5 (2.4-6.1)	0.53/0.003	25	0.67/<0.001	15
TEMRA CD8	4.3 (1.1-6.5)	0.69/<0.001	37	0.40/0.03	12
NK cells (CD16/56)	4.6 (3.1-7.7)	0.36/0.05	17	0.37/0.05	10
CD56dim	4.3 (2.9-7.3)	0.33/0.07	16	0.38/0.04	10
CD56bright	0.33 (0.21-0.46)	0.46/0.01	22	0.53/0.004	11

Rho correlation coefficient and p-values from Kendall’s tau-b test for correlation to peripheral blood concentration before and after G-CSF. Median fold increase.