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. 2021 Mar 10;11:634452. doi: 10.3389/fonc.2021.634452

Table 3.

Clinical and radiological characteristics between benign and malignant parotid gland tumors in the training and test sets.

Variable Training set (n=87) Test set (n = 38)
Benign (n=61) Malignant (n =26) P value Benign (n=27) Malignant (n =11) P value
Age (years) 52.2 ± 17.5 53.4 ± 15.4 0.781 53.9 ± 16.4 57.6 ± 10.3 0.496
Duration (months) 31.3 ± 59.2 33.2 ± 70.5 0.893 25.2 ± 56.3 11.7 ± 15.7 0.44
Maximum diameter (cm) 25 ± 11.9 28.3 ± 11.8 0.234 27.3 ± 22.7 34.5 ± 20.6 0.37
Sex [n (%)] Male 30 (49.2) 9 (34.6) 0.211 18 (66.7) 6 (54.5) 0.482
Female 31(50.8) 17 (65.4) 9(33.3) 5(45.5)
Smoking [n (%)] Yes 15 (24.6) 3 (11.5) 0.169 10 (37) 3(27.3) 0.565
No 46(75.4) 23 (88.5) 17 (63) 8 (72.7)
Distribution Single 52(85.2) 24 (92.3) 0.364 25(92.6) 10 (90.9) 0.861
Bilateral 9 (14.8) 2 (7.7) 2 (7.4) 1 (9.1)
Location Deep 4(6.6) 11 (42.3) <0.001* 4(14.8) 5 (45.5) 0.044*
Shallow 57 (93.4) 15 (57.7) 23 (85.2) 6(54.5)
Shape Round 10(16.4) 5 (19.2) 0.748 8(29.6) 2 (18.2) 0.467
Non-rounded 51 (83.6) 21 80.8) 19 (70.4) 9 (81.8)
Capsule Yes 32 (52.5) 8 (30.8) 0.063 13 (48.1) 4 (36.4) 0.508
No 29(47.5) 18 (69.2) 14(51.9) 7 (63.6)
Regularity Yes 31(50.8) 9 (34.6) 0.165 17(63) 6 (54.5) 0.63
No 30 (49.2) 17(65.4) 10 (37) 5 (45.5)
Border Clear 38(62.3) 9 (34.6) 0.018* 19(70.4) 5 (45.5) 0.149
Unclear 23 (37.7) 17(65.4) 8 (29.6) 6 (54.5)
Density Hypodense 26(42.6) 10 (38.5) 0.718 11(40.7) 4 (36.4) 0.802
Iso-hyperdense 35 (57.4) 16 61.5) 16(59.3) 7(63.6)
Enhancement Yes 55 (90.2) 24 (92.3) 0.751 25 (92.6) 11 (100) 0.354
No 6(9.8) 2 (7.7) 2(7.4) 0 (0)
Marked Enhancement Yes 40 (65.6) 20 (76.9) 0.295 17 (63) 7 (63.6) 0.969
No 21(34.4) 6 (23.1) 10(37) 4 (36.4)
Cystic degeneration Yes 28 (45.9) 11 (42.3) 0.758 12 (44.4) 6 (54.5) 0.572
No 33(54.1) 15 (57.7) 15(55.6) 5 (45.5)
Lymphadenopathy Yes 5 (8.2) 9 (34.6) 0.002* 4 (14.8) 4 (36.4) 0.139
No 56(91.8) 17 (65.4) 23(85.2) 7 (63.6)
Hemorrhage Yes 0 (0) 1 (3.8) 0.123 1 (3.7) 0 (0) 0.518
No 61(100) 25 96.2) 26(96.3) 11 (100)
Calcification Yes 2 (3.3) 2 (7.7) 0.368 1 (3.7) 0 (0) 0.518
No 59(96.7) 24 92.3) 26(96.3) 11 (100)
Heterogeneity Yes 24(39.3) 8 (30.8) 0.448 12(44.4) 2 (18.2) 0.128
No 37 (60.7) 18(69.2) 15 (55.6) 9 (81.8)

*represents P < 0.05.