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Summary of cardiac anomalies of P1 Nkx2-5 mutant mice with or without hyperoxia.
| Phenotypes | Mutant-normoxia (n = 19) | Mutant-hyperoxia (n = 22) | P value |
|---|---|---|---|
| Membranous VSD | 6 (31.6%) | 7 (31.8%) | 0.626 |
| Muscular VSD | 13 (68.4%) | 12 (54.5%) | 0.279 |
| Number of muscular VSDs per heart | 1.53 ± 0.32 | 0.68 ± 0.15 | 0.024* |
The one-sided Fisher’s exact test was used on a 2 × 2 contingency table for calculation of P values for incidence of membranous or muscular VSDs.
*P ≤ 0.05.
