Table 5.

Irwin test results of the Group D.

	Treatment	GROUP D						GROUP CONTROL D
	Observation Time	0-15′	15′	30′	1h	4h	24h	0-15′	15′	30′	1h	4h	24h
Death		0	0	0	0	0	0	0	0	0	0	0	0
Exitation	Convulsions	0	0	0	0	0	0	0	0	0	0	0	0
	Tremor	0	0	0	0	0	0	0	0	0	0	0	0
	Straub tail	0	0	0	0	0	0	0	0	0	0	0	0
	Increased activity	0	0	0	0	0	0	0	0	0	0	0	0
	Jumping	0	0	0	0	0	0	0	0	0	0	0	0
	Increased fear/startle	0	0	0	0	0	0	0	0	0	0	0	0
	Increased reactivity to touch	0	0	0	0	0	0	0	0	0	0	0	0
	Increased abdominal muscle tone	0	0	0	0	0	0	0	0	0	0	0	0
	Aggression	0	0	0	0	0	0	0	0	0	0	0	0
Steretypy	Head-twitches	0	0	0	0	0	0	0	0	0	0	0	0
	Stereotypies (Head movements)	0	0	0	0	0	0	0	0	0	0	0	0
	Stereotypies (Chewing)	0	0	0	0	0	0	0	0	0	0	0	0
	Stereotypies (Sniffing)	0	0	0	0	0	0	0	0	0	0	0	0
	Scratching	0	0	0	0	0	0	0	0	0	0	0	0
Motor	Catalepsy	0	0	0	0	0	0	0	0	0	0	0	0
	Akinesia	0	0	0	0	0	0	0	0	0	0	0	0
	Abnormal gait (rolling)	0	0	0	0	0	0	0	0	0	0	0	0
	Abnormal gait (tip-toe)	0	0	0	0	0	0	0	0	0	0	0	0
	Motor incoordination	0	0	0	0	0	0	0	0	0	0	0	0
	Loss of traction	0	0	0	0	0	0	0	0	0	0	0	0
	Loss of grasping	0	0	0	0	0	0	0	0	0	0	0	0
Sedation	Decreased activity	0	0	0	0	0	0	0	0	0	0	0	0
	Decreased fear/startle	0	0	0	0	0	0	0	0	0	0	0	0
	Decreased reactivity to touch	0	0	0	0	0	0	0	0	0	0	0	0
	Decreased abdominal muscle tone	0	0	0	0	0	0	0	0	0	0	0	0
Pain	Writhing	0	0	0	0	0	0	0	0	0	0	0	0
	Analgesia	0	0	0	0	0	0	0	0	0	0	0	0
Autonomic	Ptosis	0	0	0	0	0	0	0	0	0	0	0	0
	Exophthalmia	0	0	0	0	0	0	0	0	0	0	0	0
	Myosis	0	0	0	0	0	0	0	0	0	0	0	0
	Mydriasis	0	0	0	0	0	0	0	0	0	0	0	0
	Pilorection	0	0	0	0	0	0	0	0	0	0	0	0
	Defecation/diarrhea	0	0	0	0	0	0	0	0	0	0	0	0
	Salivation	0	0	0	0	0	0	0	0	0	0	0	0
	Lacrimation	0	0	0	0	0	0	0	0	0	0	0	0

(0) 0/6; (1) 1–2/6; (2) 3–4/6; (3) 5–6/6