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. 2021 Mar 23;325(12):1164–1172. doi: 10.1001/jama.2021.1727

Table 3. Techniques, Medications, and Confirmations of Intubations.

Variable No. (%) (n = 2964)
Application of an airway management protocol
Standard protocol
In place and used 1510 (51.0)
In place and not useda 443 (15.0)
No standard protocol in place 1009 (34.0)
Preoxygenation method (n = 2960)
Bag-valve mask 1847 (62.4)
Standard facemask 389 (13.2)
Noninvasive ventilation 344 (11.6)
High-flow nasal cannula 160 (5.4)
Anesthesia breathing circuitb 56 (1.9)
Continuous positive airway pressure 51 (1.7)
Venturi system 47 (1.6)
Nasal cannula 47 (1.6)
Otherc 19 (0.6)
Apneic oxygenation, No./total (%)d 308/2959 (10.4)
Rapid sequence induction, No./total (%)e 1727/2777 (62.2)
Cricoid pressure, No./total (%) 1120/2956 (37.9)
Induction agent, No./total (%)f 2774/2964 (93.6)
Propofol 1230 (41.5)
Midazolam 1079 (36.4)
Etomidate 527 (17.8)
Ketamine 421 (14.2)
Muscle relaxant use, No./total (%) 2095/2776 (75.5)
Rocuronium 1239 (41.8)
Succinylcholine 646 (21.8)
Vecuronium 95 (3.2)
Cisatracurium 85 (2.9)
Opioid use for intubation, No./total (%) 1415/2776 (51.0)
Method of laryngoscopy (n = 2963)
Direct laryngoscopy with Macintosh or Miller blade 2416 (81.5)
Video laryngoscopy 505 (17.1)
Other methodg 42 (1.4)
Use of intubation adjuncts (n = 1055)
Stylet 816 (77.4)
Bougie 230 (21.8)
Otherh 9 (0.8)
First method used to confirm intubation (n = 2956)
Auscultation 1711 (57.9)
Waveform capnographyi 758 (25.6)
Colorimetric carbon dioxide detectionj 222 (7.5)
Capnometryk 138 (4.7)
None 7 (0.2)
Otherl 120 (4.1)
Success, No./total (%)
First pass 2360/2958 (79.8)
Second pass 460/2958 (15.6)
Emergency front-of-neck accessm 4 (0.13)
a

Standard protocol was not used in intensive care unit (57.3%), emergency department (26.6%), ward (11.5%), and other places (4.51%), including recovery, cardiology, radiology, and endoscopy interventional rooms.

b

Anesthesia breathing circuits (eg, Mapleson C) are used outside the operating room in some centers instead of self-inflating bags (bag-valve mask). While they require a source of oxygen to work, they provide a lower resistance alternative in spontaneously breathing patients.

c

Included invasive mechanical ventilation (for patients with self-extubation) and preoxygenation via bag-valve and an extraglottic airway device.

d

Oxygen administration during laryngoscopy or fiberoscopy.

e

Rapid onset induction without positive pressure ventilation between induction and laryngoscopy.

f

Proportion of patients receiving each subcategory of induction agent. Some patients received more than 1 induction drug while others received an opioid as induction agent or underwent awake fiberoptic intubation under local anesthesia.

g

Included direct laryngoscopy with McCoy blade and fiberoptic intubation. Nasotracheal intubations were performed in 0.8% of patients.

h

Included tube exchange catheter, lighted stylet, and Magill forceps.

i

Monitor provided the graphic measurement of exhaled carbon dioxide plotted against time.

j

Device uses a photochemical reaction to detect the presence of carbon dioxide in the exhaled air.

k

Provides only the absolute value of carbon dioxide concentration in the exhaled air.

l

Included chest x-ray and fiberoscopy.

m

One cricothyroidotomy, 1 percutaneous tracheostomy, and 2 surgical tracheostomies.